Pregnenolone

Produced in the mitochondria throughout the body from cholesterol, pregnenolone is the base material of all human steroid manufacture, including DHEA, progesterone, testosterone and estrogen. It appears to block the effects of cortisol, preventing stress. Pregnenolone stimulates brain NMDA receptors. These receptors, which decline with age, play an important role in the function of synapses and neurons, influencing learning and memory. Pregnenolone levels are directly correlated with cognitive ability. Pregnenolone levels decline with age.

Pregnenolone's anti-aging benefits may include reduction of stress, reduction of arthritic inflammation, potential maintenance of memory capability, improved mood, positive outlook and well-being and improved sleep patterns.

Pharmacology: Chemical; 3-alpha-hydroxy-5-beta pregbeb-20-one.

Side Effects and Contraindications: There have been reports of rash occurring with use, but otherwise there are few side effects. There are no known contraindications, but people with prostate conditions should be monitored carefully.

Distribution: Pregnenolone is available in 5mg, 10mg, 20mg, 25mg, 30mg, 50mg and 100mg capsules.

Note: Pregnenolone is set for a resurgence of interest and could become more popular than DHEA.

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