WHAT IS IT?
Idebenone is an analogue of Coenzyme Q10.
WHAT DOES IT DO?
In most respects, Idebenone shares its traits with Coenzyme Q10.
Like Coenzyme Q10 is might be useful for aging. It differs from
it in some important ways, which may make it more useful. Under
certain circumstances, Coenzyme Q10 (CoQ10) may become a pro-oxidant.
These circumstances are conditions in which hypoxia or lack of
oxygen occurs. In cases of shock, heart attack, stroke, or poor
circulation, CoQ10 auto-oxidizes and unleashes massive amounts
of various free radicals that damage delicate tissues and because
CoQ10 is necessary for electron transport and ATP (chemical energy)
production, cellular death may ensue. Idebenone, on the other
hand, suppresses free radicals and continues ATP production in
hypoxic situations. This may make it a useful supplement for individuals
at risk for those conditions.
Other important traits of Idebenone not shared
by CoQ10 include the ability to raise the brain's serotonin levels
like the SSRI antidepressants (Prozac) and it also increases the
brain levels of nerve growth factor. Another trait is to protect
the myelin sheath from damage as well as the mitochondria that
has important implications in Multiple Sclerosis.
The ability to enhance serotonin production
occurs even under less than optimal conditions such as those whose
diet contains little L-Tryptophan.
Naturally, nerve growth is a desired result
in many conditions. In Alzheimer's Disease, for example, several
studies show dose dependent improvements when compared to placebo
as measured by different tests when taking Idebenone. An abstract
said, "Treatment with idebenone was found effective on memory,
attention, and orientation and in slowing down the natural progressive
worsening of the disease."
The following conditions may benefit from Idebenone:
Brain enhancement as a nootropic, stroke, Alzheimer's, dementia,
surgical candidates, cardiovascular, MS, other demyelination conditions,
aging, depression, Friedreich's Ataxia, and liver problems.
Few adverse reactions have been noted with this substance even
at doses of 900 mg daily.
Idebenone is an analog (variation) of Coenzyme Q10, a powerful
anti-oxidant biochemical known also as "ubiquinone"
and most commonly as CoQ10. This substance is the energy producing
unit of our body cells. Every process in our bodies requires CoQ10.
Without CoQ10 life stops.
Benefits of CoQ10 in autism are:
- Supplies energy necessary for proper Immune
- Strong antioxidant power to help prevent free radical damage
- Provides energy for the natural detoxification process in the
- Helps fight off Candida and bacterial and viral infections
- Helps correct immunodeficiencies
- Enhanced Focus
- Mood Elevation
- Desire to engage in more conversation
Idebenone supplies all of the same benefits
as CoQ10 plus some distinct advantages based on its more complex
chemical structure. Though very similar in chemical make-up to
CoQ10, its longer chain organic structure gives it extra powerful
anti-oxidant properties making it a more effective "free
radical quencher" resulting in less cell and tissue damage.
Some leading doctors treating autism believe
that Idebenone offers three very distinct advantages over CoQ10
in supplementing developmental disorders.
- Studies show that Idebenone enhances
brain structure and function
- Its superior anti-oxidant properties protect body organs more
- Offers protection against excitatory amino acid neurotoxicity
from ingestion of these ingredients through the diet (Examples:
MSG, artificial sweeteners, canned soups and meats, spices, etc.)
to Anti-Aging Medicine Index