Adrafinil acts to stimulate brain activity only when stimulation
is required. Modafinil is the latest, more potent analogue of
Adrafinil. Both drugs act on brain Alpha 1 post synaptic receptors
and make them more susceptible to norepinephrine, thus increasing
alertness and concentration. They do not appear to affect other
Adrafinil and Modafinil's anti-aging benefits have been increased
and improved alertness and concentration, improved thought clarity
and short-term memory and increased reaction speed, including
Pharmacology: Chemical Name: 2-(Diphenylmethyl) sulfinyl acetohydroxamic
acid. Molecular Formula: C(15)H(15)NO(3)S. Molecular Weight: 289.4CAS
Registry: 63547 13-7. Adrafinil is an alpha-adrenergic agonist
chemically related to Modafinil. It is given by mouth as a CNS
Stimulant in doses of 60mg to 1.2g daily.
Side Effects and Contraindications: Side effects include an increase
in liver enzyme levels and, therefore, usage should be monitored.
Other side effects include headaches, stomach pain, minor skin
irritations, inner tension and mild agitation, or aggression.
People with epilepsy, liver or kidney impairment, or those using
tranquilizers, should avoid Adrafinil and Modafinil. Caution is
advised, if used in combination with norepinephrine-stimulating
agents such as Yohimbine.
Distribution: Adrafinil is supplied in 300mg tablets under the
trade name Olmifon. Modafinil is supplied under the trade name
Modiodal in 100mg tablets.
Notes: Modafinil is superior to Adrafinil in its action. However,
most patients will usually experience improvement with Adrafinil.
Modafinil is a very recent addition and is considerably more expensive
to Anti-Aging Medicine Index