| 5HTP
5-Hydroxy-Tryptophan
also known
as Oxitriptan |
5HTP,
Oxitriptan is converted into the neurotransmitter serotonin in
the body. Serotonin is a key factor in mood regulation, and reduction
of depression and anxiety. Lack of serotonin has been linked to
compulsive disorders, especially the overeating of carbohydrates.
Serotonin is also the precursor to the pineal gland's production
of melatonin. As serotonin levels decline with age supplementation
with the amino acid L-tryptophan, or the drug 5HTP
, Oxitriptan is beneficial. Oxytriptan's (5HTP) advantage is that,
unlike L-tryptophan, it is used solely by the brain for the production
of serotonin, and thus more effective in increasing serotonin
levels.
Oxitriptan's (5HTP's) anti-aging benefits may
include the prevention and treatment of depression, maintenance
of serotonin levels as the body ages, prevention and treatment
of compulsive disorders like overeating, improved daytime alertness
and treatment of insomnia.
Pharmacology: 5-hydroxy-tryptophan (in the body
the amino acid L-tryptophan is converted to 5-hydroxy-tryptophan
by a B3 dependent enzyme and then converted to serotonin by a
B6 dependent enzyme). Synonyms: 5HTP; L-5-Hydroxytryptophan;
Ro-0783/B. Chemical Name: L 2-Amino-3-(5-hydroxy-1-H-indol-3-yl)propionic
acid. Molecular Formula: C(11)H(12)N(2)O(3) Molecular Weight:
220.2 CAS Registry: 4350 09-8 (Oxitriptan); 56-69-9 (DL-5-hydroxytryptophan).
Side Effects and Contraindications: Side effects
include nausea and mild gastric discomfort. Patients suffering
serious renal insufficiency, or hypersensitivity to oxitriptan
should avoid the drug. Patients treated with alpha methyldopa
and methysergide, which block the peripheral decarboxylization
of oxitriptan, should take oxitriptan with caution.
Distribution: Oxitriptan is available in 50mg
or 10mg tablets under the trade names Cincofarm, Levotonine, Levothym,
Oxyfan, Serotonyl TM, Serovit, Telesol, Trimag, Tript-OG, Tript-Oh,
Triptene TM and Triptum TM.
Note: A potentially effective, safe and non-toxic
method of improving serotonin levels.
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